PUBLICATIONS
Niyangoda, S., Kearney, J., Hettiarachchi, P., Theismann, J., Shigemoto, A., Hickey, E. E., Burdette, S. C., Johnson, M. A.* “Quantitative Control of Zn2+ Photorelease: A Step toward Decoding Mechanisms of Subsecond Metal Signaling in the Brain,” Anal Chem., 2025, 97(38):20887-20896. https://doi.org/10.1021/acs.analchem.5c03208
Li M, Sanderson BJ, Hackett JL, Niyangoda SS, Gong H, Johnson MA, Wang ZW, “Comparative Transcriptomic Profiling of Drug Metabolizing Enzymes and Drug Transporters in Rabbit Ocular Sub-tissues, Liver, and Duodenum,” Drug Metab. Dispos. 2025, 53(7):100099 https://doi.org/10.1016/j.dmd.2025.100099
Hettiarachchi P, Shigemoto A, Hickey EE, Burdette SC, Johnson MA*, “Zinc-dependent modulation of dopamine release and uptake is altered in Parkinson’s disease model zebrafish.” ACS Chem. Neuro. 2025, 16(10):1872-1882. Note: Featured on journal coverhttps://doi.org/10.1021/acschemneuro.4c00864
Kirckof A, Kneller E, Vitale EM, Johnson MA, Smith AS. “The effects of social loss and isolation on partner odor investigation and dopamine and oxytocin receptor expression in female prairie voles.” Neuropharmacology. 2025, 267:110298. https://doi.org/10.1016/j.neuropharm.2025.110298
Garcia KJ, Theismann JT, Schneider TD, LeComte RS, Jarmolowicz DP, Johnson MA* “Doxorubicin Treatment Has a Biphasic Effect Over Time on Dopamine Release and Impulsive Behavior in Wistar Rats.” Naunyn-Schmiedeberg's Archives of Pharmacology. 2025, 398(7):8497-8509. https://doi.org/10.1007/s00210-024-03766-5
Vitale EM, Tbaba AH, Sanchez S, Hale L, Kenkel WM, Johnson MA, Smith AS.
“Pair bond quality influences social conditioned place preference expression, passive coping behavior, and central oxytocin receptor expression following partner loss in male prairie voles.”J. Soc Neurosci. 2024,19(4):273-286. https://doi.org/10.1080/17470919.2024.2428598
Hettiarachchi P, Niyangoda S, Shigemoto A, Solowiej IJ, Burdette SC, Johnson MA*, “Caged Zn2+ Photolysis in Zebrafish Whole Brains Reveals Subsecond Modulation of Dopamine Uptake.” ACS Chem Neurosci. 2024,15(4):772-782. https://doi.org/10.1021/acschemneuro.3c00668
Tian J, Stucky CS, Wang T, Muma NA, Johnson MA*, Du H.*, “Mitochondrial Dysfunction Links to Impaired Hippocampal Serotonin Release in a Mouse Model of Alzheimer's Disease,”J Alzheimers Dis. 2023, 93(2):605-619. https://doi.org/10.3233/jad-230072
Jarosova R, Woolfolk SK, Martinez-Rivera N, Jaeschke MW, Rosa-Molinar E, Tamerler C*, Johnson MA*, “Spatiotemporal Imaging of Zinc Ions in Zebrafish Live Brain Tissue Enabled by Fluorescent Bionanoprobes,” Molecules 2023, 28(5):2260. https://doi.org/10.3390/molecules28052260
Hettiarachchi P, Johnson MA*, “Characterization of D3 Autoreceptor Function in Whole Zebrafish Brain with Fast-Scan Cyclic Voltammetry” ACS Chem Neurosci. 2022, 13(19):2863-2873. Note: Sutton Family Research Impact Award (November 2022) https://doi.org/10.1021/acschemneuro.2c00280
Stucky CS and Johnson MA*, "Improved Serotonin Measurement with Fast-Scan Cyclic Voltammetry: Mitigating Fouling by SSRIs, " J. Electrochem. Soc. 2022,169, 045501. Note: Sutton Family Research Impact Award (June 2022) https://doi.org/10.1149/1945-7111/ac5ec3
Jarosova R*, Niyangoda SS, Hettiarachchi P, Johnson MA*,” Impaired Dopamine Release and Latent Learning in Alzheimer's Disease Model Zebrafish,” ACS Chem Neurosci. 2022, 13(19):2924-2931. https://doi.org/10.1021/acschemneuro.2c00484
Hettiarachchi P, Niyangoda SS, Jarosova R, Johnson MA*, “Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson's Disease Model Zebrafish,” Chem Res Toxicol. 2022, 35(11):1974-1982. https://doi.org/10.1021/acs.chemrestox.2c00150
Jarosova R and Johnson MA*, “Optimized Sawhorse Waveform for the Electrochemical Measurement of Oxytocin in Zebrafish,” Anal. Chem. 2022, 94(6):2942–2949. Note: Sutton Family Research Impact Award (March 2022) https://doi.org/10.1021/acs.analchem.1c04879
Jarasova R., Kaplan S.V., Field, T.M., Givens R.S., Sendaheera S.N., Johnson M.A.* "In Situ Electrochemical Monitoring of Caged Compound Photochemistry: An Internal Actinometer for Substrate Release," Anal. Chem. 2021, 93(5):2776-2784 https://doi.org/10.1021/acs.analchem.0c03452
Jarmolowicz D.P., Gehringer R., Lemly S.M., Sofis M.J., Kaplan S.V., Johnson M.A. "5-Fluorouracil impairs attention and dopamine release in rats," Behavioral Brain Research 2019, 362:319-322 https://doi.org/10.1016/j.bbr.2019.01.007
Kaplan S.V., Limbocker R.A., Levant B., Johnson M.A.* “Regional differences in dopamine release in the R6/2 mouse caudate putamen” Electroanalysis 2018, 30(6):1066-1072 https://doi.org/10.1002/elan.201700827
Field T.M., Shin M., Stucky C.S., Loomis J., Johnson M.A.* “Electrochemical Measurement of Dopamine Release and Uptake in Zebrafish Following Treatment with Carboplatin,” ChemPhysChem 2018, 19(10):1192-1196 https://doi.org/10.1002/cphc.201701357
Shin M., Field T.M., Furgerson M.N., Stucky C.S., Johnson M.A.* “Ex Vivo Measurement of Electrically Evoked Dopamine Release in Zebrafish Whole Brain.” ACS Chem Neurosci. 2017, 8(9):1880-1888 https://doi.org/10.1021/acschemneuro.7b00022
Sofis M.J., Jarmolowicz D.P., Kaplan S.V., Gehringer R.C., Lemley S.M., Garg G., Blagg B.S., Johnson M.A. “KU32 prevents 5-fluorouracil induced cognitive impairment.” Behav Brain Res. 2017, 329:186-190. Note: Featured in major news outlets, including: Science Daily, Medical News Today, UPI https://doi.org/10.1016/j.bbr.2017.03.042
Kaplan S. V., Limbocker R. A., Divis J. L., Osterhaus G. L., Newby M. D., Sofis M. J., Jarmolowicz D. P., Newman B. D., Mathews T. A., Johnson M.A.* “Impaired Brain Dopamine and Serotonin Release and Uptake in Wistar Rats Following Treatment with Carboplatin.”ACS Chem. Neurosci. 2016, 7(6):689-699. ACS Editor’s Choice Award, Featured on the journal cover, Featured in Chemical & Engineering News, 94(21), May 23, 2016. Featured in other major news outlets, including:Science Daily, MedicalResearch.com, MedicalxPress, Neuroscience News. https://doi.org/10.1021/acschemneuro.5b00029
Shin M., Kaplan S.V., Raider K.D., Johnson M.A.* “Simultaneous measurement and quantitation of 4-hydroxyphenylacetic acid and dopamine with fast-scan cyclic voltammetry,” Analyst. 2015, 140(9):3039-3047. https://doi.org/10.1039/c4an02007c
Sun, M., Johnson, M.A.* “Measurement of total antioxidant capacity in sub-μL blood samples using craft paper-based analytical devices,” RSC Advances. 2015, 5(69):55633-55639. https://doi.org/10.1039/c5ra06479a
Sun M., Kaplan S. V., Gehringer R. C., Limbocker R. A., Johnson M. A.*“Localized drug application and sub-second voltammetric dopamine release measurements in a brain slice perfusion device,” Anal. Chem. 2014, 86(9):4151-4156. https://doi.org/10.1021/ac5008927
Kaplan, S. V., Fowler S. C., Johnson M. A.* “Measurements of Dopamine Release and Uptake in Huntington’s Disease Model Rodents” (2014) Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience ed. G.S. Wilson and A.C. Michael (World Scientific Publishing: Hackensack, NJ) pp 311-329.
Shin M, Kaplan SV, Newby M, Johnson M. A.* Conference Report: Pittcon 2013: microfluidics, electrochemistry, and much much more. Bioanalysis. 2013, 5(16):1965-7 https://doi.org/10.4155/bio.13.160
Johnson M. A.* In vivo electrochemical measurements: past, present and future. Bioanalysis. 2013, 5(2):119-22 https://doi.org/10.4155/bio.12.322
Ortiz, A. N., Osterhaus, G. L., Lauderdale, K. A., Selley, P. S., Fowler, S. C., von Horsten, S., Riess, O., and Johnson, M. A.* “Motor function and dopamine release measurements in transgenic Huntington's disease model rats,” Brain Res. 2012, 1450:148-56. https://doi.org/10.1016/j.brainres.2012.02.042
Ortiz, A. N., Kurth, B. J., Osterhaus, G. L., Johnson, M. A.*, “Impaired dopamine release and uptake in R6/1 Huntington's disease model mice,” Neurosci Lett. 2011, 492(1):11-14 https://doi.org/10.1016/j.neulet.2011.01.036
Ortiz, A. N., Oien, D. B., Moskovitz, J., Johnson, M. A.* “Quantification of reserve pool dopamine in methionine sulfoxide reductase A null mice.” Neuroscience. 2011, 177:223-9 https://doi.org/10.1016/j.neuroscience.2011.01.001
Fulks, J. L., O'Bryhim, B. E., Wenzel, S. K., Fowler, S. C., Vorontsova, E., Pinkston, J. W., Ortiz, A. N., Johnson, M. A.* “Dopamine release and uptake impairments and behavioral alterations observed in mice that model fragile X mental retardation syndrome,” ACS Chem Neurosci. 2010, 1(10):679-690. https://doi.org/10.1021/cn100032f
Oien, D. B., Ortiz, A. N., Rittel, A. G., Dobrowsky, R. T., Johnson, M. A., Levant, B, Fowler, S. C., Moskovitz, J. “Dopamine D2 receptor function is compromised in the brain of the methionine sulfoxide reductase A knockout mouse,” J. Neurochem. 2010, 114, 51-61. https://doi.org/10.1111/j.1471-4159.2010.06721.x
Ortiz, M. A., Kurth, B. J., Osterhaus, G. L., Johnson, M. A.* “Dysregulation of intracellular dopamine stores revealed in the R6/2 mouse striatum,” J. Neurochem. 2010, 112, 755-761. https://doi.org/10.1111/j.1471-4159.2009.06501.x
Miller, B.R., Walker, A. G., Fowler, S. C., von Horsten, S., Riess, O., Johnson, M. A., Rebec, G. V. “Dysregulation of coordinated firing patterns in striatum of freely behaving transgenic rats that model Huntington’s disease,” Neurobiology of Disease, 2010, 37, 106-113. https://doi.org/10.1016/j.nbd.2009.09.013
Fowler S. C., Miller B. R., Gaither T. W., Johnson M. A., Rebec G. V., “Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington’s disease,” Behav. Brain Res. 2009, 202(1):130-7. https://doi.org/10.1016/j.bbr.2009.03.022
Kraft, J. C., Osterhaus, G. L., Ortiz, A. N., Garris, P. A., Johnson, M. A.*, “In vivo dopamine release and uptake impairments in rats treated with 3-nitropropionic acid,” Neuroscience, 2009, 161(3):940-9. https://doi.org/10.1016/j.neuroscience.2009.03.083
Oien, D. B., Osterhaus, G. L., Latif, S. A., Pinkston, J. W., Fulks, J., Johnson, M. A., Fowler, S. C., Moskovitz, J. “MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels,” Free Rad. Biol. Med. 2008, 45(2):193-200. https://doi.org/10.1016/j.freeradbiomed.2008.04.003
Wilson, G. S. and Johnson, M. A. “In vivo electrochemistry: what can we learn about living systems?” Chem. Rev. 2008, 108(7), 2462-2481. https://doi.org/10.1021/cr068082i
Jain, H. D., Zhang, C., Zhou, S., Zhou, H., Ma, J., Liu, X., Liao, X., Deveau, A. M., Dieckhaus, C. M., Johnson, M. A., Smith, K. S., Macdonald, T.L., Kakeya, H., Osada, H., Cook, J.M. “Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein,” Bioorg. Med. Chem. 2008, 16(8), 4626-4651. https://doi.org/10.1016/j.bmc.2008.02.050
Johnson, M. A., Villanueva, M., Haynes, C. L., Seipel, A. T, Buhler, L. A., and Wightman, R. M., "Catecholamine exocytosis is diminished in the R6/2 mouse model of Huntington’s disease," J. Neurochem., 2007,103(5), 2102-10. https://doi.org/10.1111/j.1471-4159.2007.04908.x
Johnson, M. A., Rajan, V., Miller, C. E., and Wightman, R. M. “Dopamine release is severely compromised in the R6/2 mouse model of Huntington’s disease,” J. Neurochem., 2006, 97(3), 737-746. https://doi.org/10.1111/j.1471-4159.2006.03762.x
Schonhoff, C. M., Matsuoka, M., Tummala, H., Johnson, M. A., Estevez, A., Kamaid, A., Ricart, K., Hashimoto, Y., Gaston, B., Macdonald, T. L., Xu, Z., and Mannick, J. B. “Aberrant denitrosylation in amyotrophic lateral sclerosis,” Proc. Nat. Acad. Sci.(USA), 2006 Feb 14;103(7), 2404-2409. https://doi.org/10.1007/s12035-013-8562-z
Johnson, M. A. and Macdonald, T. L. “Accelerated CuZn-SOD-mediated oxidation and reduction in the presence of hydrogen peroxide,” Biochem. Biophys. Res. Commun. 2004, 324(1), 446-450. https://doi.org/10.1016/j.bbrc.2004.09.066
Heien, M. L. A. V., Johnson, M. A., and Wightman, R. M. “Resolving neurotransmitters detected by fast-scan cyclic voltammetry," Anal. Chem. 2004, 76(19), 5697-5704. https://doi.org/10.1021/ac0491509
Zhao, S, Smith, K. S., Deveau, A. M., Dieckhaus, C. M., Johnson, M. A., Macdonald, T. L., and Cook, J. “Biological activity of the tryptostatins and their diastereomers on human carcinoma cell lines,” J. Med. Chem. 2002, 45(8), 1559-1562 https://doi.org/10.1021/jm0155953
Snyder, A. H., Mcpherson, M. E., Hunt, J. F., Johnson, M., Stamler, J. S., and Gaston, B. M. “Acute effects of aerosolized S-nitrosoglutathione in cystic fibrosis,” Am. J. Respir. Crit. Care Med. 2002, 165, 1-5. https://doi.org/10.1164/ajrccm.165.7.2105032
Lipton, A. J., Johnson, M. A., Macdonald, T., Lieberman, M. W., Gozal, D., Gaston, B., Ponka, P., Kim, S. “S-nitrosothiols control breathing and oxygen homeostasis,” Redox Report 2002, 7(1), 5-7. https://doi.org/10.1179/135100002125000118
Johnson, M. A., Macdonald, T. L., Mannick, J. B., Conaway, M. R., and Gaston, B. “Accelerated S-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper, zinc-superoxide dismutase,” J. Biol. Chem. 2001, 276, 39872-39878. https://doi.org/10.1074/jbc.m102781200
Lipton, A. J., Johnson, M. A., Macdonald, T., Lieberman, M. W., Gozal, D., and Gaston, B. “S-nitrosothiols signal the ventilatory response to hypoxia,” Nature 2001, 413, 171-174. Featured in News and Views. https://doi.org/10.1038/35093117
Dieckhaus, C. M., Roller, S. G., Johnson, M. A., Smith, K. S., Miller, T. A., Sofia, R. D., and Macdonald, T. L. “Felbamate metabolite patient urinalysis to monitor potential drug-induced idiosyncratic reactions,” Epilepsia. Accepted, then withdrawn for proprietary reasons.
Zapien, D. Z. and Johnson, M. A. “Direct electron transfer of ferritin adsorbed at bare gold electrodes,” J. Electroanal. Chem. 2000, 494(2), 114-120.